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Hi Tim, it takes about 3-4 weeks before your body starts using ketones effectively and you become keto-adapted.

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Although several small studies have evaluated the role of continuous infusion of loop diuretics in patients with heart failure, these studies have been underpowered to address clinical questions.

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Our findings demonstrate that the use of non-potassium-sparing diuretics was associated with increased risk of mortality and hospitalization in a wide spectrum of ambulatory chronic systolic and diastolic HF patients.

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Disease processes that in the normal population could be treated adequately in the outpatient setting might require hospitalization in the ADHF patient.

In the OPTIME-CHF trial, 949 patients admitted to the hospital with ADHF were randomized to standard medical therapy with the addition of either milrinone or a placebo.

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In the patient who is hospitalized with ADHF, intravenous rather than oral administration is recommended, because of greater and more consistent bioavailability of the drug.

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Retinal lesions (eg, retinal hemorrhage, retinal detachment, arterial tortuosity, focal or diffuse retinal edema) were found in 80% of hypertensive cats in one study.

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