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Permanently discontinue epoetin alfa in patients who develop PRCA following treatment with epoetin alfa or other erythropoietin protein drugs.

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Bush RS: The significance of anemia in clinical radiation therapy.

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Cancer patients who use epoetin injection must read about and become familiar with the ESA APPRISE Oncology Program.

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ESA and iron therapy in chronic kidney disease: a balance between patient safety and hemoglobin target.

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When including those who completed treatment, the overall sustained virologic rates were 36% in the pegylated interferon plus ribavirin arm and 28% in the standard interferon plus ribavirin alone arm.

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Patients in these trials were randomized to one of two treatment arms: “immediate” or “delayed” treatment with epoetin or darbepoetin after Hb fell to a prespecified threshold.

ESA therapy may reduce dialysis efficacy (due to increase in red blood cells and decrease in plasma volume); adjustments in dialysis parameters may be needed.

Historical clinical and economic consequences of anemia management in patients with end-stage renal disease on dialysis using erythropoietin stimulating agents versus routine blood transfusions: a retrospective cost-effectiveness analysis.

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Another indirect technique uses a combination of 5 markers of enhanced erythropoiesis (haematocrit, reticulocyte haematocrit, percentage of macrocytic red blood cells, serum EPO, sTfr) to detect rhEPO.

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