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Day two and I'm feeling a little weird but better than yesterday. I'm on 50 mg to start. I've been on Zoloft before and don't remember feeling like this. Last time I felt better almost instantly. I been off it for about 6 years. I'll stick with it this time because I know it does work.

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I have now been on this medication for 6 days and I'm seeing a terrific change not 100% yet but it's giving me light and life back again. I am loving this change I didn't think I was helpable. I thought I was too far gone but slowly am making a come back.

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The interaction of stressful life events and a serotonin transporter polymorphism in the prediction of episodes of major depression: a replication".

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Treatment with Sertraline hydrochloride and any concomitant serotonergic agents should be discontinued immediately if the above events occur and supportive symptomatic treatment should be initiated.

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In particular, the efficacy of l-tryptophan, a precursor of serotonin, and of pyridoxine, which serves as a cofactor in the conversion of tryptophan into serotonin, also favors serotonin deficiency as a cause of PMDD.

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Thus sertraline multiple dose pharmacokinetics appear to be unaffected by renal impairment (see PRECAUTIONS).

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And when referring to Prozac and other SSRI's and sufficient historical context please remember, this is not a book about SSRI's we are discussing, but an article about sertraline.

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Data Sources: Data were obtained via the MEDLINE database in an English-language search spanning the period 1965 to May 2002 and using the search terms bupropion, bupropion SR, and antidepressants, as well as from the manufacturer's bupropion databases.

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In addition to randomized controlled studies comparing CBT with other treatment modalities, dismantling studies seem warranted to identify the active ingredients in this treatment.

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The conditions and duration of exposure to sertraline hydrochloride varied greatly, and included (in overlapping categories) clinical pharmacology studies, open and double-blind studies, uncontrolled and controlled studies, inpatient and outpatient studies, fixed-dose and titration studies, and studies for multiple indications, including major depressive disorder and PMDD.

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To put it differently generics have identical active ingredients and their pharmacological effects are the same, as those of their brand-name equivalents.

However, prior to initiating treatment with an antidepressant, patients with depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder; such screening should include a detailed psychiatric history, including a family history of suicide, bipolar disorder, and depression.

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