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Hematology: Small decreases in hemoglobin and hematocrit occur frequently in hypertensive patients treated with ACEON, but are rarely of clinical importance.

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Absolute stroke event rates were low; the number needed to treat to prevent one stroke over the course of 5 years with intensive blood pressure management is 89.

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PVWMC may affect cognition more than DWMC.

Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults.

Given the small number of events of end-stage renal disease (29 in the intensive-control group and 53 in the standard-control group), the benefits with respect to this end point should be interpreted with caution and studied further in future trials.

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