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Severe muscle cramps, after almost one year on 10 mg/day Crestor, for familial hypercholesterolemia of 6. Not overweight, exercise and eat well. Stopped Crestor and resolved within 1 week. 2 months later, liver tests normal but cholesterol borderline high restarted with 5 mg every other day along with co enzyme Q 100 mg/day and had taken 2 weeks of Coenzyme Q to build up stores prior to this. Severe cramps resumed within 1 week.

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You are aware that this is a liver disease community, and that people with liver disease are not supposed to drink.

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The study found that Asian-Americans showed an increased risk for developing muscle damage from Crestor use.

Also reducing the sugars in your body also seems to help.

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Letter to FDA Renewing Call for Crestor to Be Removed From Market.

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My doctor reviewed my laboratory results today and tried to convince me that I need to take Crestor for high cholesterol.

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your doctor may do blood tests to check your liver before you start taking crestor

We reduced him to 1 capsule a day and added in Ubiquinol COQ10 and it helped.

These side effects may go away during treatment as your body adjusts to the medicine.

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This drug may also reduce the risk of heart attack, stroke, or other health problems in patients with risk factors for heart disease.

It is important that a healthcare provider know about all of the drugs, supplements, and foods that a person has ingested recently so that the PT and INR results are interpreted and used correctly.

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Initially, I thought it might be just a coincidence that I developed this pain while taking Crestor, because it wasn't listed as a side effect in the literature but really, there was no other reason for such a symptom.

Take that to your Dr.

And other side effects include mild nausea or stomach pain, stomach upset, heartburn, constipation, bloating, gas.

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If you're convinced these small effects are real, are they meaningful to you?

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You are about to access AstraZeneca historic archive material.

Crestor is used to and triglycerides (types of fat) in the blood.

With my Cardiochek I found that my cholesterol was at 158 with the 5mg dose and decided to stay at that level.

This may be the worst medicine in the world, deifnitely the worst I have ever taken.

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It works by blocking an enzyme that is needed by the body to make cholesterol, so this reduces the amount of cholesterol in the blood.

A generic drug is actually its brand-name equivalent, although it doesnt bear the original trademark and looks slightly different.

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The usually lowers LDL by 20%, also tends to increase HDL in small amounts, but in your case it had the opposite effect on the HDL; it is not clear why this happenned.

After three weeks working with the doctor trying to control the rash which he thought was eczema I lay awake one itchy night and read the patient leaflet about Crestor and it said a known but uncommon side effect was extremely itchy skin with raised red lumps, said it's an ellergic reaction and stop taking immediately.

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Once the job eased down, the BP went down, and he had to good sense to take me off it and I have never had high BP ever since.

If you have any questions concerning CRESTOR, please visit or contact AstraZeneca at 1-800-CRESTOR.

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Refuse a cholesterol testing, and ask for a CRP, which shows how much inflammation is going on in your body.

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The balance sheet for statins looks like this: These drugs cut the risk of heart attack, angina (chest pain), stroke, and death from cardiovascular disease by 30%.

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Patients taking Crestor also had higher levels of good HDL.

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February 2010 found that side effects of statins like Crestor may increase the risk of diabetes by 9%.

The FDA prescribing information, which was updated in 2012, reports rare events of fatal and non-fatal liver failure in Crestor patients.

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All Crestor side effects are dependent upon dose.

Other health factors, such as family history, diabetes, high blood pressure, or if you smoke, or are overweight, may also play a role in the formation of plaque in arteries.

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Rosuvastatin joins atorvastatin and fluvastatin as the statins that have not demonstrated a health benefit to the patients that use them in terms of reducing the serious cardiovascular consequences of high cholesterol such as a first or second heart attack or stroke.

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If you have high cholesterol, your doctor will probably start you on 5 mg or 10 mg tablet taken once daily.

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Crestor, but not as bad as what I had seen with the Lipitor.

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Although Crestor was first introduced in 2003 for the limited use among patients with bad cholesterol and a history of heart disease, the FDA expanded approval in 2010 to include prescriptions for otherwise healthy individuals who may be given the drug for prevention of heart attacks, strokes and deaths.

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When CRESTOR was coadministered with fenofibrate no clinically significant increase in the AUC of rosuvastatin or fenofibrate, was observed.

Do not drink large amounts of alcohol while taking rosuvastatin.

The cost-cutting announcement came as AstraZeneca rolled out first-quarter results, with earnings per share slightly ahead of analyst estimates.

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Serum cholesterol and triglycerides increase during normal pregnancy, and cholesterol products are essential for fetal development.

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About one-third of the patients benefited from increasing their dose from 20 mg to 40 mg with further LDL lowering of greater than 6%.

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In the clinical trials for Crestor, the most common side effects reported by participants taking Crestor included headache, pain in muscles (myalgia), abdominal pain, abnormal (asthenia), and nausea.

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Crestor has recently changed its dosage recommendation for some people.

The three major components of this process are (1) changes in the caliber of blood vessels and the rate of blood flow through them (hemodynamic changes); (2) increased capillary permeability; and (3) leukocytic exudation.

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Crestor therapy should be discontinued if markedly elevated creatine kinase levels occur or myopathy is diagnosed or suspected.

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Ongoing controlled clinical trials of Crestor and other statins, epidemiologic studies of the safety and side effects of Crestor, and ongoing pharmacovigilance by FDA will continue to provide information on the balance of risks and benefits of Crestor and other members of this important class of drugs.

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Statins: Some studies have linked the long-term use of cholesterol-lowering drugs known as statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), with lower PSA levels.

Patients also need to undergo regular lab and medical tests to monitor their progress while taking either Crestor or Lipitor.

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FDA to decline Crestor approval in 2003.

The FDA decided not to completely pull the drugs from the market because the potential side effects were found to weigh far less than the benefits these cholesterol-lowing drugs have.

Your doctor may want to adjust the dose of one or both medicines.

COM is for educational use only.

Please seek medical advice before starting, changing or terminating any medical treatment.

In the United States, where the drug has only been on the market for a little more than 5 months, a 39-year-old woman, taking only 20 milligrams a day, died of rhabdomyolysis and renal insufficiency.

We need to find out why statins cause diabetes and, ideally, through genomics we could determine who is at risk for this important side effect.

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CRESTOR 20 mg reduced LDL-C significantly more than atorvastatin 20 mg and 40 mg; pravastatin 20 mg and 40 mg; simvastatin 20 mg, 40 mg, and 80 mg.

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Although it took a hysterectomy for me to achieve this, I'm very grateful to be feeling well and working again (and back in school, too).

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It has to pay AstraZeneca 39% of net sales on the drug till pediatric exclusivity expires July 8 of that year.

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Clearly, 2016 will be a challenging year due to the loss of exclusivity for Crestor in the United States.

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Step 5) If you already have some muscle weakness or pain, take 600 mg per day of alpha-lipoic acid.

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Think I will try on for two weeks and off for two weeks and see where it gets me the next time I see my doc.

Little confused -- why is your husband going back to Niaspan in light of the flushing, welts, etc?

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My main reason relates to the nature of the randomized controlled trials we rely on for evidence.

Crestor is in a class of cholesterol medications called statins.

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The recent medical news that Crestor, lipitor in this dosage has been shown to cause kidney failure and death IN SOME USERS has made me re-think a bit.

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Because another drug in this class passes into human milk and because HMG-CoA reductase inhibitors have a potential to cause serious adverse reactions in nursing infants, women who require CRESTOR treatment should be advised not to nurse their infants.

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Don't just look at the makers web sites, go back a good 10 pages and you will find people on forums like this who are having even worse side effects from these drugs that should never have been approved in the first place.

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Crestor is commonly associated with musclar side effects such as pain, cramping, stiffness and spasms.

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In 2005, the FDA issued a Crestor warning because it can cause rhabdomyolysis, a condition characterized by atrophying skeletal muscle tissue.

Lord that we still can find highly trained doctors like you, that are not afraid to stand up against all the misinformed doctors in the world.

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None of these patients was below 8 years of age.

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To determine whether rosuvastatin 80 mg once weekly produced comparable lipid and high-sensitivity C-reactive protein (hsCRP) changes to atorvastatin 10 mg daily, when measured at key points after last dose.

Of course you will need to speak with your physician first.

And his success and results with heart patients are the best in the world.

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Properly discard this product when it is expired or no longer needed.

Your health care provider will perform blood work on you to see if the Crestor is affecting the liver.

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Because another drug in this class passes into breast milk, and because HMG-CoA reductase inhibitors have the potential to cause serious adverse reactions in nursing infants, women who require CRESTOR treatment should be advised not to nurse their infants.

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